I purchased a very early model of the Logitech wireless kb/mouse combo (been around a year since then), here's some of the problems/difficulties I've encountered:1) Batteries on the mouse die too fast to my liking...even though I don't use it much (see #2 below for reason).
2) The accuracy of the wireless mouse is not as good as a wired one
3) Although technically you can use your kb and/or mouse across the room, there's usually too much interference to make it really viable unless you're pointing the kb/mouse at the wireless "box."